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Liqiang Xi, M.D.

Current Position
Research Assistant Professor
Mount Sinai School of Medicine
New York, NY.
Professional Address
Mount Sinai School of Medicine
Department of Oncology/Hematology
One Gustave Levy Place, Box 1079
New York, NY
(212) 241-3010
Education
2002 Master of Information Science, School of Information Sciences, University of Pittsburgh, Pittsburgh, PA

1990 Master of Public Health, Chinese Academy of Preventive Medicine, Beijing, China

1984 M.D, Harbin Medical University, China

Academic
Appointments

2004-present Research Assistant Professor, Mount Sinai School of Medicine, New York

2001-2004 Research Associate, Department of Surgery, School of Medicine, University of Pittsburgh

1991-1994 Research Assistant, Department of Toxicology, Institute of Occupational Medicine, Chinese Academy of Preventive Medicine

1984-1987 Medical Doctor, Miyun County Branch, Center for Disease Control and Prevention of China, Beijing, China

Postdoctoral Training
1997-2001 Postdoctoral Fellow, Graduate School of Public Health, University of Pittsburgh

1994-1997 Postdoctoral Fellow, School of Public Health, University of California at Berkeley

Professional Membership
American Association for Cancer Research
Association for Molecular Pathology
Publications

Liqiang Xi , Michael C. Coello, Virginia R. Litle, Siva Raja, William E. Gooding, Samuel A. Yousem, Talal El-Hefnawy, Rodney J. Landreneau, James D. Luketich, and Tony E. Godfrey. (2006) A Combination of Molecular Markers Accurately Detects Lymph Node Metastasis in NSCLC Patients. Clinical Cancer Research, in press.

Liqiang Xi , William Gooding, Kenneth McCarty, Tony E. Godfrey, and Steven J. Hughes. (2006) Identification of mRNA Markers for Molecular Staging of Lymph Nodes in Colorectal Cancer. Clinical Chemistry, 52, 520-523.

Steven J. Hughes, Liqiang Xi, Siva Raja, William Gooding, David J. Cole, William E. Gillanders, Keidi Mikhitarian, Kenneth McCarty, Susan Silver, Jesus Ching, William McMillan, James D. Luketich, and Tony E. Godfrey. (2006) A Rapid, Fully-Automated, Molecular-Based Assay Accurately Analyzes Sentinel Lymph Nodes for the Presence of Metastatic Breast Cancer. Annals of Surgery, 243, 389–398.

Liqiang Xi , James Lyons-Weiler, Michael C. Coello, Xin Huang, William E. Gooding, James D. Luketich, Tony E. Godfrey. (2005) Prediction of Lymph Node Metastasis by analysis of Gene Expression Profiles in Primary Lung Adenocarcinomas. Clinical Cancer Research, 11, 4128-4135.

Siva Raja, Jesus Ching, Liqiang Xi, Steven J. Hughes, Ronald Chang, Wendy Wong, William McMillan, William E. Gooding, Kenneth S. McCarty Jr., Melissa Chestney, James D. Luketich, and Tony E. Godfrey. (2005) A New Technology for Automated, Rapid, and Quantitiative PCR or RT-PCR Clinical Testing. Clinical Chemistry, 51, 882-890.

Robert L. Ferris*, Liqiang Xi*, Siva Raja, Jennifer L. Hunt, Jun Wang1,2, William E. Gooding, Lori Kelly, Jesus Ching, James D. Luketich, Tony E. Godfrey. (2005) Molecular Staging of Cervical Lymph Nodes in Squamous Cell Carcinoma of the Head and Neck. Cancer Research, 650, 2147-2156. (* co-first authors).

Xi, L , Luketich, JD, Raja, S, Gooding, W, Litle, VR, Coello, MC, Finkelstein, SD, Chestney, ML, Landreneau, RJ, Hughes SJ, Godfrey, TE.(2005)Molecular Staging of Lymph Nodes from Patients with Esophageal Adenocarcinoma. Clinical Cancer Research, 11, 1099-1109.

Wang J, Xi L, Gooding W, Godfrey TE, Ferris RL. (2005)Chemokine receptors 6 and 7 identify a metastatic expression pattern in squamous cell carcinoma of the head and neck. Adv Otorhinolaryngol . 62, 121-33.

Jun Wang, Liqiang Xi, Jennifer L. Hunt, William Gooding, Theresa L. Whiteside, Zhuo Chen, Tony E. Godfrey, and Robert L. Ferris. (2004) Expression Pattern of Chemokine Receptor 6 (CCR6) and CCR7 in Squamous Cell Carcinoma of the Head and Neck Identifies a Novel Metastatic Phenotype. Cancer Research 64, 1861-1866

Hayes RB, Zhang L, Swenberg JA, Yin SN, Xi L, Wiencke J, Bechtold WE, Yao M, Rothman N, Haas R, O'Neill JP, Wiemels J, Dosemeci M, Li G, Smith MT. (2001) Markers for carcinogenicity among butadiene-polymer workers in China. Chem Biol Interact. 135-136, 455-64.

Hayes RB, Zhang L, Yin S, Swenberg JA, Xi L, Wiencke J, Bechtold WE, Yao M, Rothman N, Haas R, O'Neill JP, Zhang D, Wiemels J, Dosemeci M, Li G and Smith MT. (2000) Genotoxic markers among butadiene polymer workers in China. Carcinogenesis 21(1), 55-62.

Zhang L, Rothman N, Wang Y, Hayes RB, Yin S, Holland N, Dosemeci M, Wang Y, Kolachana P, Lu W, Xi L, Li G, Smith MT. (1999) Benzene increases aneuploidy in the lymphocytes of exposed workers: A comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells. Environmental and Molecular Mutagenesis 34, 260-268.

William L. Bigbee, Richard D. Day, Stephen G. Grant, Phouthone Keohavong, Liqiang Xi, Lifang Zhang, and Roberta B. Ness. (1999) Impact of maternal lifestyles on newborns hprt mutant frequencies and molecular spectrum-Initial results from the Prenatal Exposures and Preeclampsia Prevention (PEPP) Study. Mutation Research 431, 279-289.

Julia B. Scheerer, Liqiang Xi, Geremy W. Knapp, R. Woodrow Setzer, William L. Bigbee, James Fuscoe. (1999) Quantification of illegitimate V(D)J recombinase-mediated mutations in lymphocytes of newborns and adults. Mutation Research 431, 291-303.

Titenkoholland N. Shao JS. Zhang LP. Xi LQ. Ngo HL. Shang N. Smith MT. (1998) Studies on the genotoxicity of molybdenum salts in human cells in vitro and in mice in vivo. Environmental and Molecular Mutagenesis. 32, 251-259.

Smith MT. Zhang LP. Wang YX. Hayes RB. Li GL. Wiemels J. Dosemeci M. Titenkoholland N. Xi LQ. Kolachana P. Yin SN. Rothman N. (1998) Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene. Cancer Research. 58, 2176-2181.

Liqiang Xi , Luoping Zhang, Yunxia Wang, and Martyn T. Smith. (1997) Induction of chromosome-specific aneuploidy and micronuclei in human lymphocytes by metabolites of 1,3-butadiene. Carcinogenesis, 18, 1687-1693.

Nathaniel Rothman, Martyn T. Smith, Richard B. Hayes, Robert D. Traver, Betty-ann Hoener, Sharan Campleman, Gui-Lan Li, Mustafa Dosemeci, Martha Linet, Luoping Zhang, Liqiang Xi, Sholom, Wacholder, Wei Lu, Kathleen, B. Meyer, Nina Titenko-Holland, James T. Stewart, Songnian Yin, and David Ross. (1997) Benzene Poisoning, a Risk Factor for Hematological Malignancy, Is Associated with the NQO1 609 C ® T Mutation and Rapid Fractional Excretion of Chlorzoxazone. Cancer Research, 57, 2839-2842.

Hayes, R.B., Xi L., Bechtold W.E., Rothman N., Yao M., Henderson R., Zhang L., Smith M.T., Zhang D., Wiemels J., Dosemeci M., Yin S. and O'Neill J.P. (1996) hprt Mutation frequency among workers exposed to 1,3-butadiene in China. Toxicology, 113, 100-105.

Rothman, N., Smith M.T., Hayes R.B., Li G.L., Irons R.D., Dosemeci M., Haas R., Stillman W.S., Linet M., Xi L.Q., Bechtold W., Wiemels J., Campleman S., Zhang L., Quintana J.E., Holland N.T., Wang Y.Z., Lu W., Kolachana P., Meyer K.B. and Yin S.Y. (1996) An epidemiologic study of benzene's early biologic effects in heavily exposed workers in Shanghai, China. Environmental Health Perspectives, Supplements, 104, 1365-1370.

Rothman, N., Li G.L., Dosemeci M., Bechtold W., Marti G.E., Wang Y.Z., Linet M., Xi L.Q., Wei L., Smith M.T., Holland N., Zhang L.P., Blot W., Yin S.N. and Hayes R.B. (1996) Hematotoxicity among Chinese workers heavily exposed to benzene. American Journal of Industrial Medicine, 29, 236-246.

Rothman, N., Haas R., Hayes R.B., Li G.L., Wiemels J., Campleman S., Quintana P.J., Xi L.J., Dosemeci M., Titenko-Holland N., Meyer K.B., Lu W., Zhang L., Bechtold W., Wang Y.Z., Kolachana P., Yin S.N., Blot W. and Smith M.T. (1995) Benzene induces gene-duplicating but not gene-inactivating mutations at the glycophorin A locus in exposed humans. Proc Natl Acad Sci U S A, 92, 4069-73.

Yin, S.N., Li G.L. and Xi L.Q. (1994) Study on the chromosome image process system. J. of Hygiene Research (Chinese), 23, 186-188.

Xi, L.Q. , Luo Y.S., Guo W.H., Li G.L. and Yin S.N. (1994) Application of chromosome image process system in the several studies. J. of Hygiene Research (Chinese), 23, 189-190.

Xi, L.Q. , Wu W.A., Huang M.Y., Li W., Chen S.Y. and Cai S.X. (1993) Epidemiological study on female reproduction after exposure to chloroprene. J. of Hygiene Research (Chinese), 22, 321-326.

Xi, L.Q. (1992) Reproductive and embryo toxicity of chloroprene (review). Chinese J. of Industrial Medicine, 5, 29-33.

Cai, S.X., Huang M.Y., Xi L.Q., Li Y.L., Qu J.B., Kawai T., Yasugi T., Mizunuma K., Watanabe T. and Ikeda M. (1992) Occupational dimethylformamide exposure. 3. Health effects of dimethylformamide after occupational exposure at low concentrations. Int Arch Occup Environ Health, 63, 461-8.

Kawai, T., Yasugi T., Mizunuma K., Watanabe T., Cai S.X., Huang M.Y., Xi L.Q., Qu J.B., Yao B.Z. and Ikeda M. (1992) Occupational dimethylformamide exposure. 2. Monomethylformamide excretion in urine after occupational dimethylformamide exposure. Int Arch Occup Environ Health, 63, 455-60.

Xi, L.Q. , Cai S.X., Huang M.Y., Wu W.A., Chen S.Y., Li W. and Su J. (1991) Epidemiological study on male reproduction after exposure to chloroprene. Chinese J Ind Hyg and Occup Dise, 9, 202-210.

 
Last Updated: 03/13/2006

Tony E. Godfrey, Ph.D.
Associate Professor of Surgery and Biomedical Genetics



The James P Wilmot Cancer Center
University of Rochester Medical Center
New York, NY



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